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This saliva dilutes the medication, reduces the concentration gradient driving absorption, and triggers the swallowing reflex
doi: 10.1016/j.bbrc.2009.12.075 25 ArakawaMMitaTAzumaKEbatoCGotoHNomiyamaTet al

Exposure was approximately twofold higher with a 40 mg versus a 20 mg dose, and there was no difference in exposure for the 40 mg dose between healthy individuals and those with T2D

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Recent research published by Digbi Health and conducted in collaboration with leading physicians from the Division of Gastroenterology and Nutrition at Allegheny Health Network and Northwestern Medical School demonstrates how food-as-medicine can lead to measurable changes in the gut microbiota, which in turn affects these critical metabolic pathways
