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FDA Zepbound Prescribing Information, revised February 2026Supports: Tirzepatide half-life described as approximately 5 days and approximately 5 to 6 days in the label

Aliment Pharmacol Ther 2002

As the SELECT trial nears completion, a similar large trial was launched in autumn 2022, but this one involves a new wrinkle on GLP-1 receptor agonism that appears to yield even greater weight loss
