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China: The CFDA regulates incretin mimetics, with Liraglutide being approved in 2018
The concern stems from the fact that these drugs promote cellular proliferation in the intestines, potentially leading to tumorigenesis
All off label, of course
Another common hurdle is step therapy, which forces you to try and fail with cheaper, older medications before the plan will cover a newer, more expensive one like a GLP-1
Interestingly, these neurons do not contribute to tonic cardiovascular regulation
