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Surgery (rare) For perforation, obstruction, or uncontrolled bleeding Complications Bleeding most common Perforation medical emergency Penetration ulcer extends into adjacent organs (pancreas) Obstruction due to scarring or edema G-D-U G Gastric ulcer (stomach) D Duodenal ulcer (first part of small intestine) U Ulcer symptoms: epigastric pain, nausea, heartburn

The use of gut-hormone receptors agonists as new therapeutic options for obesity and some of its related comorbidities, such as type 2 diabetes, has resulted in an unprecedented efficacy in the medical management of people living with obesity (PLWO)

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