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A prefilled syringe (PFS) is a sterile, single-use syringe that comes preloaded with a specific drug dose, designed for injection without requiring prior compounding pharmacies or manual filling by a healthcare provider

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Although much research has focused on mechanisms within the central nervous system to explain this pain suppression 8 , we hypothesize that additional mechanisms occurring in the peripheral nervous system are based on hormonal regulation during digestion

A research guide with an honest review of the evidence base