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May interact with medications metabolized by CYP3A4 enzymes Not recommended: During pregnancy, breastfeeding, or with certain liver conditions Fiber supplements are safe for most people but require gradual introduction to minimize bloating and gas

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Notably, treatment with a GLP-1RA effectively alleviated hyperphagia and body weight gain, improved glucose tolerance, and regulated circulating metabolic hormones in Bbs5 / mice

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