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In summary, the GLP-1 receptor remains an interesting and noteworthy target for the pharmacotherapy of central nervous system diseases, not only those related to neurodegeneration and substance abuse, but GLP-1RA drugs may also prove effective as adjunctive therapies in the treatment of mood disorders such as depression

History of gallbladder disease: Trulicity may cause acute (short-term) gallbladder disease

These are dose-dependent and typically decrease over time

Call your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools increased risk of low blood sugar (hypoglycemia), especially those who also take medicines for diabetes such as insulin or sulfonylureas

Others are pure marketing hype