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Drugs@FDA: Approval updates for GLP-1 receptor agonists for diabetes and chronic weight management

Absolute MACE risk estimates for semaglutide vs comparators In concordance with the relative risk analysis, the absolute risk estimates for MACE with semaglutide vs comparators varied across the CV risk spectrum, with a trend for the largest absolute risk reduction in subjects at medium-to-high CV risk, as evidenced by the lowest NNT (111) being observed at a medium-to-high CV risk score of 0.483 (Fig

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While EMA is investigating the issue, the vaccines can continue to be used in line with the approved product information