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The therapeutic range extends to 15 mg

The SELECT trial (2023) demonstrated a significant reduction in major cardiovascular events for people with obesity and established CVD on semaglutide
In some cases, the side effects from the pill version may feel more intense, McGowan said, because the medication hits the stomach all at once and can trigger nausea

These adverse reactions occurred more commonly on RYBELSUS than on placebo and occurred in at least 5% of patients treated with RYBELSUS
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