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For study 1 (weight loss study of GLP-1MK-801 relative to monotherapies), mice were randomly divided into four experimental groups ( n = 8 mice per group) with similar mean body weights and assigned to receive once-daily s.c
doi: 10.3390/ijms141123045 82 IshibashiYMatsuiTOjimaANishinoYNakashimaSMaedaSet al

This helped to reveal the way peptides in the body are produced (Sims, Carr, Oram)

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Compared to control, significant reductions in intracranial pressure were seen acutely at 2.5 h and 24 h, but also at 12 weeks [101]
