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doi: 10.2337/dc18-S008 21 ShiLJiYJiangXZhouLXuYLiYet al

Trajectory of weight regain after cessation of GLP-1 receptor agonists: a systematic review and nonlinear meta-regression

Interestingly, because the activation of OB GLP-1R is sufficient to decrease glucose in both RD and WD mice, our data support the absence of GLP-1 resistance in the OB of obese mice

Current clinical guidance restricts these medications to adults, with most evidence concentrated in populations aged 3075 years

Also, check with your doctor if it turns into chronic diarrhea, as adverse effects may have occurred