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It should explain why semaglutide is medically necessary for your specific case, reference your diagnosis codes and comorbidities, cite the clinical trial evidence (STEP 1 showed 14.9% mean weight loss, NEJM 2021

Hydration needs: daily fluid intake should reach 8 to 12 cups as these medications reduce thirst signals

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For patients with PCOS, long-term treatment offers additional benefits

They represent the favorable end of the response distribution that real-world users can access with optimal conditions
