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In the UK, licensed weight loss medications, including orlistat and GLP-1 receptor agonists such as semaglutide (Wegovy), work through distinct mechanisms and are prescribed under specific NICE eligibility criteria, and June 2026 brought the first oral GLP-1 for weight loss, the Wegovy pill, a once-daily tablet

Stoldt J, Cox C, Matusz E

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Rybelsus comes as an oral tablet in three doses: 3 mg, 7 mg, and 14 mg
