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Description
Most cases were mild and didn't lead to participants stopping treatment

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Fatigue that persists beyond the initial titration phase warrants investigation for other causes, including nutritional deficiencies common in bariatric patients

Tirzepatide (Mounjaro, Zepbound) targets two, GLP-1 and GIP

However, using an ECD-binding antibody Fab fragment (Fab7F38) for co-crystallization, we successfully crystallized the GLP-1RPF-06372222Fab7F38 complex
