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In addition to its effects on insulin and glucagon, GLP-1RAs work on the brain for an anorexigenic effect by promoting feelings of satiety and modulating energy homeostasis

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They help the body control blood sugar levels

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One mechanism that this may be achieved is through a pathological skew toward hedonic and away from homeostatic controls of energy balance in obesity, potentially mediated by deregulated central GLP-1 signalling (a role for GLP-1 in the pathophysiology of clinical obesity)

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