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doi: 10.1016/S2213-8587(13)70214-6 39
Dorsomedial hypothalamus (DMH) and preoptic area (POA) The DMH and POA are a functional complex of nuclei in the hypothalamus, which are involved in the regulation of feeding, drinking, body-weight, and circadian rhythms

Retatrutide works by targeting three different receptors: By combining these three actions, Retatrutide addresses multiple aspects of weight control at once

Most gastrointestinal side effects occur during dose escalation and reduce significantly over time
