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Renal function should be monitored, as severe gastrointestinal adverse effects can lead to dehydration and acute kidney injury, particularly in patients with pre-existing renal impairment

doi: 10.1016/j.cbi.2019.06.001 186 SallesGNCalioMLHolscherCPacheco-SoaresCPorcionattoMLoboAO

However, lean body mass also includes organs, bones, and skin

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