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The difference lies in the magnitude: injections typically produce stronger appetite reduction because higher drug concentrations reach your brain and digestive organs

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Bethel MA, Patel RA, Merrill P, Lokhnygina Y, Buse JB, Mentz RJ, et al
Reduced Appetite Control : Tirzepatide reduces appetite, but alcohol can increase cravings and reduce self-control, leading to overeating

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But the magnitude does not approach what retatrutide achieves
