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This finding was so striking that Wegovy is now indicated for overweight and obese patients with heart disease

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

GLP-1 also affects non-hunger related (hedonic) feeding by targeting brain areas involved in reward, motivation and addiction, such as the VTA, NAcc, lateral septum [701,741,744,745], and PVT [704]

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Dulaglutide-EMA assessment report
