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doi: 10.3389/fphar.2026.1736380 Received 10 November 2025 Revised 20 January 2026 Accepted 21 January 2026 Published 10 February 2026 Volume 17 - 2026 Edited by Madhusudan Prasad Singh, All India Institute of Medical Sciences Raipur, India Reviewed by Hemasri Velmurugan, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), India Prachi Arunima, All India Institute of Medical Sciences Raipur, India Updates Copyright 2026 Wali, Rangraze, Khan, Mufti, El-Tanani and Rizzo

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This did not present a risk in the researchers sample because they excluded people with body-mass indices (BMIs) lower than 23 (the World Health Organization considers BMIs 18.5 24.9 normal), and most study participants had a BMI of 30 or more (classified as obese)

These three factors combine to create the most efficient absorption surface available outside of injection