exendin 4 tirzepatide Replacement of the C-terminal Trp-cage of exendin-4 with a fatty acid improves therapeutic utility GLP-1RECEPTOR AGONISTS Primary structures of

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Future research should characterize GIPR with single-cell ocular transcriptomics, directly compare Tirzepatide with pure GLP-1 RAs for IOP and retinal outcomes across metabolic contexts, and incorporate ophthalmic endpoints in cardiometabolic trials to better define the risk-benefit profile

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[DOI] [PubMed] [Google Scholar] 59.Macgregor AM, Greenberg RA