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Exenatide ER (Bydureon) A long-acting GLP-1 receptor agonist that supports glycaemic control and weight management through delayed gastric emptying and increased satiety

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The trial demonstrated that approximately 35% of semaglutide-induced weight loss was due to loss of lean mass and further demonstrated that combining semaglutide with trevogrumab with or without garetosmab helped preserve lean mass while increasing loss of fat mass