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They simultaneously suppress glucagon, the hormone that raises blood sugar between meals

Lactate is the critical substrate for histone lactylation, a novel epigenetic modification associated with inflammation [16] and fibrotic diseases [17, 29]

The risk of pancreatitis can be minimized by addressing and mitigating risk factors from previous episodes, regulating the rate of weight loss by adjusting the GLP-1 receptor agonist dose and the content and frequency of meals, closely monitoring patients during GLP-1 receptor agonist therapy, and implementing appropriate precautionary measures