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2011 Sep-Oct;23(5):220-6 2

Plast Reconstr Surg

50 mg/kg twice daily for 28 days raised oxidative muscle fibers and OXPHOS proteins

Retatrutide is a triple receptor agonist, affecting three hormones related to obesity: (3) Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide 1 (GLP-1) Glucagon (GCG) Receptor agonists interact with receptors like natural substances, causing a biological response
Most evidence comes from observational studies and case reports, which suggest potential benefit but cannot establish definitive efficacy or safety profiles
