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But side effects may briefly return or intensify for a few days as your body adjusts to the higher dose

That part is on us

This combination supports faster recovery from injuries involving muscles, tendons, ligaments, and joints

Current prescribing information for Ozempic notes that it delays gastric emptying, and Zepbounds prescribing information lists nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, reflux, and belching among common side effects

Published: Aug 13, 2025 Written by Klarity Editorial Team Published: Aug 13, 2025 Key takeaway: Joint pain during GLP-1 treatment particularly with tirzepatide is a recognized side effect linked to rapid fat loss, muscle changes, and inflammatory responses