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they are also responsive to ovarian steroids (74)

living with diabetes and over 100 million affected by obesity, the rising demand for these drugs has caused global shortages

Eli Lilly reports positive Phase 3 trial results for obesity drug retatrutide Published: 10:16 11 Dec 2025 EST Eli Lilly and Co (NYSE:LLY) reported positive topline results from its Phase 3 TRIUMPH-4 trial evaluating its obesity treatment retatrutide in adults with obesity and knee osteoarthritis

For example, if a patient is managing hypertension and diabetes, their clinician can adjust their weight management plan considering how GLP-1s may affect blood pressure medication and how it can improve their A1C levels

Dizziness Weakness Drowsiness or fatigue Slow heartbeat Low blood pressure Dry mouth, skin, or eyes Headache Upset stomach Diarrhea or constipation Heart block Cold hands and feet Weight gain Less common side effects include: Depression Shortness of breath, wheezing, or trouble breathing, with people who have asthma or Raynauds syndrome facing a higher risk of these adverse effects High blood sugar (hyperglycemia) Trouble sleeping, including insomnia and nightmares Swelling of the hands or feet (edema), specifically in those who take carvedilol (Coreg) Sexual and erectile dysfunction Are There Any Risks