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Why does tirzepatide cause less nausea than semaglutide if it is more potent

GLP-1 and GLP-1(7-36) amide: influences on basal and stimulated insulin and glucagon secretion in the mouse

Both compounds suppressed caloric intake, promoted a marked weight loss, improved glucose tolerance and reduced plasma cholesterol levels
[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Lindqvist A., Shcherbina L., Fischer A.-H.T., Wierup N

High-salt foods can worsen these side effects, so limit foods like processed snacks, canned soups, deli meats, and salty condiments
