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SGLT-2 Inhibitors: Consistent Use and Continued Caution SGLT-2 Inhibitor Usage Among Registry Participants Then: 2% Now: 2% SGLT-2 inhibitors reduce blood glucose by helping the kidneys to excrete excess glucose through urine

In the future, Retatrutide may be considered for individuals who meet specific health criteria, such as those living with obesity or weight-related conditions, but suitability would depend on personal medical factors

Other GLP-1s like exenatide (Byetta, now discontinued), liraglutide (Victoza), and dulaglutide (Trulicity) reduced plasma levels of oral contraceptives by up to 45 percent and delayed absorption by up to 3.5 hours, though not enough to cause the birth control to fail

We note that HRAs are a promise by an employer to pay up to a specified amount and that many employees will not receive the full amount of their HRA in a year, so adding the employer premium contribution amount and the HRA contribution represents an upper bound for employer liability that overstates the amount that is actually expended

CAROLYN BRAMANTE: Yes, I'd love to give a little context