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[DOI] [PubMed] [Google Scholar] 173.Nahra R., Wang T., Gadde K.M., Oscarsson J., Stumvoll M., Jermutus L., Hirshberg B., Ambery P

Accumulated evidence has shown that the RAAS is no longer considered to act just as an endocrine system, but also as a paracrine, autocrine and intracrine system

More companies are incorporating these medications into their treatment programs, but given that this is a new landscape with both proven and emerging uses, companies must measure vital signs, monitor secondary effects, and integrate behavior change into their care plans as they transition patients off these drugs over time

J Clin Endocrinol Metab 99(7):24772485

New Formulations: Efforts are underway to create more convenient formulations, including longer-acting injectables that may only require monthly administration and improved oral versions
