glp-1 cancer risk Semaglutide: What we know about safety and GLP-1 drugs cut breast cancer
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They do not harm tissue or permanently alter the structure or function of your digestive system
100102 In addition, inflammatory cytokines are reportedly involved in CYP gene expression, with the reduced cytokine levels-mediated by GLP-1 RA administration may alter CYP gene expression, potentially leading to changes in the pharmacokinetics of co-administered drugs (Figure 3)
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[DOI] [PubMed] [Google Scholar] 130
5.4.2 Effects on liver Despite the lack of expression of GIPR (191) and GLP-1R (192, 193) in hepatocytes, both GIP and GLP-1 have indirect effects on hepatic lipid and glucose metabolism (194)
