can glp 1 cause anxiety What is GLP-1 & Does it Affect Weight & Cognition? Ozempic: GLP-1s Linked to 42%

Its FDA approved for long-term weight management in adults with obesity and for those who are overweight with a related health condition, such as high blood pressure

doi: 10.1056/NEJMoa2206038.

For risk-averse individuals who want to explore GLP-1 support without the side effect burden of medications, this gentler profile represents a legitimate reason to start with the supplement approach

Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats

If this line of thinking is applied to the mesolimbic GLP-1R activation, it is plausible that while NAc GLP-1R activation is associated with a suppression of the dopamine signal, the VTA GLP-1R reduce reward behavior via another mechanism