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The FDA-approved Prescribing Information for tirzepatide (Mounjaro and Zepbound) includes specific warnings and precautions regarding pancreatic safety, reflecting ongoing pharmacovigilance for this medication class

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The cost-effectiveness of oral semaglutide versus empagliflozin in Type 2 diabetes in Denmark

IR is associated with chronic low-grade inflammation, hypothalamicpituitaryadrenal (HPA) axis dysregulation, impaired neuroplasticity, mitochondrial dysfunction, and altered reward processing mechanisms that may contribute to core depressive features such as anhedonia, cognitive slowing, and emotional dysregulation

doi: 10.1001/jamaneurol.2017.1658