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The SUPRPASS-4 trial (262), involving 2002 participants with high-risk cardiovascular profiles followed for up to 104 weeks, showed no difference in 4-MACE events (cardiovascular death, myocardial infarction, stroke, and hospitalization for unstable angina) with tirzepatide compared to insulin glargine (HR 0.74

"A drug does not educate you on how to eat properly," cautioned Suzy Badaracco, a registered dietician and president of the food trends forecasting firm Culinary Tides

One feature making this trial particularly interesting is the choice of medicine

You pay cash, though HSA and FSA funds are accepted

The American Academy of Sleep Medicine (AASM) said it supports the FDA's approval of Zepbound as a sleep apnea treatment but emphasized that it is not an option for everyone