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doi: 10.1016/j.ajem.2024.01.010

Notably, PTX and YM-25890 treatment had no effect on 15 mM KCl-stimulated calcium mobilization (Figure 2D), suggesting that the inhibitory effects observed on hGPR17L-mediated calcium signaling are not due to toxicity or non-specific effects on calcium signaling

The consistent appetite suppression at this dose allows for sustained caloric reduction without the mental struggle that typically accompanies dieting

Maintaining a stable temperature and preventing moisture exposure is crucial to avoid premature degradation

You can report any suspected side effects directly to the MHRA through the Yellow Card Scheme at yellowcard.mhra.gov.uk, contributing to ongoing medication safety monitoring