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S.Van WittenbergheN.EricssonM.GriffinG

2021: STEP Changes the Game The STEP trials brought semaglutide into the spotlight

This meta-analysis was conducted based on the P (Participants), I (Interventions), C (Comparisons), O (Outcomes), and S (Study design) (PICOS) principles

Source: Employer Benefit Research Institute April 16, 2026 GLP-1 medications for obesity carry a well-documented discontinuation problem, and stopping them typically means regaining weight and the return of cardiometabolic risk factors

Buse JB, Weyer C, Maggs DG
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