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59 Recently, the SURMOUNT-5 trial demonstrated that tirzepatide was superior to semaglutide in obese patients without diabetes with respect to reductions in body weight and waist circumference at week 72

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Surprisingly in two months lost 3 kg and insulin dose drastically reduced and achieved euglycemia which was so erratic with insulin, gliclazide and Metformin

The good news is that combining these therapies is generally considered safe when properly monitored by qualified healthcare providers