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These medications, including liraglutide, semaglutide, and dulaglutide, are primarily used to manage blood sugar levels and appetite in diabetes patients

Mechanistically, FSH vaccination treatment inhibited lipid biosynthesis by inactivating PPAR adipogenic signaling pathway and simultaneously enhancing adipocyte thermogenesis via upregulating UCP1 (uncoupling protein 1) expression in both visceral and subcutaneous adipose tissues (74)

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We think the benefit of these drugs may extend to all patients and this will be studied as part of our ongoing trial. Cohen also says that people who have a normal weight or are underweight could experience too much weight loss as a GLP-1 side effect

Like all GLP-1 treatments, it only works alongside diet and activity changes