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However, most previous NMA studies have compared specific drugs (e.g., pioglitazone and rosiglitazone) or combinations of drug regimens (e.g., rosiglitazone+losartan, rosiglitazone+ metformin) rather than drug classes [38,39,42]

Effect of liraglutide therapy on liver fat content in patients with inadequately controlled type 2 diabetes: the Lira-NAFLD study

Previous MOF were equally prevalent (9.6%) in both groups

BCBS Massachusetts, BCBS Michigan, BCBS Vermont, Independence Blue Cross in Pennsylvania, Blue Cross of Idaho, and Highmark (which operates across Pennsylvania, West Virginia, New York, and Delaware) all implemented restrictions

47 SGLT2-I approved in the US for the treatment of T2DM include canagliflozin (Invokana, 2013), dapagliflozin (Farxiga, 2014), and empagliflozin (Jardiance, 2014)