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another method tried was addition of polyethylene glycol (PEG) to form PEGylated GLP-1

Real-world use of similar GLP-1 receptor agonists like liraglutide and semaglutide extends beyond 5 years in some patients

However, given the liver's crucial role in many aspects of the metabolism of lipids, carbohydrates, and proteins, it is appreciated that any injury to the liver will potentially impact several organs 6

doi: 10.1016/j.clinthera.2008.03.005

Pyridoxine is an inexpensive ingredient, and the additional compounding steps are straightforward
