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The most common side effects reported in trials include: Digestive issues Nausea (the most frequently reported side effect) Vomiting Diarrhoea Constipation Stomach pain or discomfort Loss of appetite Other reported effects Fatigue or tiredness Injection site reactions (redness, swelling, or irritation) Most side effects tend to be worse when starting the medication or increasing the dose, and often improve as your body adjusts

I work with hundreds of Bariatric physicians, Surgeons bariatric practices and that data is much more seen in clinical trial now the information is out and theres a second generation third generation of GLP one out and coming out

The potential for innovative formulations suggests a promising future for this class of drugs

We also expand on these findings by showing that KO of CNS GIPR can sensitize the response to GLP-1R agonism and that CNS GIPR is necessary for the maximal weight loss response to mGIPR-Ab/GLP-1

In the clinical trial, patients on the highest dose lost about 25 lbs or approximately 11% of their body weight over 72 weeks