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Cotadutide, but not liraglutide improved hepatic parameters and metabolic dysfunction-associated steatohepatitis (MASH) with similar weight loss with 200 g cotadutide compared to 1.8 mg liraglutide and greater with 300 g cotadutide versus 1.8 mg liraglutide [47]
According to ADA guidelines, these medications are preferred second-line agents for patients with established atherosclerotic cardiovascular disease

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It is a question that the team hopes to explore in follow up studies focused specifically on substance use disorder.