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Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment

The comparison between phentermine and semaglutide , phentermine and tirzepatide , and phentermine and GLP-1 medications broadly consistently shows the GLP-1 class producing greater weight loss with a more favorable long-term safety profile
6.0% reduction in relative fat mass

GLP-1 RA Semaglutide (Rybelsus) : 3 ., 7 ., 14

Colostrum adds to the benefits by enhancing immune function and promoting gut healing