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The whole system just is set up to basically kick in when its a complete catastrophe, Linda said
28,36 Theoretically, the substitution of Gly 22 with Ala would make the -helix more stable, but increments in the affinity and activity were not found
& Rajagopalan, S
Svendsen B, Pedersen J, Albrechtsen NJW, Hartmann B, Torng S, Rehfeld JF, et al
Kidney Int 98:769777
