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A two-tailed P -value below 0.05 was considered statistically significant

Extended Data Figure 4 Effects of binding pocket mutations on potency of NAMs

List of adverse reactions of SSIBs included in this study

With GLP-1 medications: You pharmacologically reduce the dopamine-seeking behavior the food noise quiets but because the same pathways handle all reward and motivation non-food joys can get quieter too

This is significant because it opens up access to providers who specialize in GLP-1 prescribing but do not bill Medicare directly
