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GLP-1 RAs significantly reduced the risk of MACE compared with placebo (hazard ratio [HR] 0.87, 95% confidence interval [CI] 0.770.98) in HF coexisting with T2DM

Originally developed for diabetes and weight loss, GLP-1 medications may help quiet the brains reward circuitry, muting the intense craving signals associated with Substance Use Disorders
Oral semaglutide 25mg achieved average weight loss of 16.6% at 64 weeks, while orforglipron 36mg achieved 12.4% at 72 weeks

The relationship between obesity and depression is partly dependent on metabolic health status: A nationwide inpatient sample database study

So, is Zepbound the same as Ozempic
