semaglutide and general anesthesia Are Serious Risks of Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia Semaglutide and Type 2 Diabetes
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Semaglutide works by slowing gastric emptying and signaling fullness to the brain, which can trigger nausea during the first weeks of treatment

52 The effect of semaglutide on HRQoL in HFpEF, particularly social and physical function as measured by the KCCQ, is mediated at least in part by the effect on weight reduction
This doesn't necessarily indicate risk, but it does mean we're relying on individual safety profiles and clinical judgment

Using supplements as part of a stepped care approach can make sense for many people, though some clinicians recommend starting with medication when the risk from excess weight is high
