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The drug should be prescribed along with diet and exercise for both the diabetes and weight-management(2 Trusted Source FDA Green-Lights Tirzepatide, Marketed as Zepbound, for Chronic Weight Management Go to source)

Compounded semaglutide is prescribed by clinicians as part of an overall treatment plan that may include nutrition and lifestyle guidance

The body adapts to the appetite-suppressing and gastric-slowing effects over time, and each four-week period allows that adaptation to occur before the next increase

As this layer diminishes with weight loss, the body loses some of its natural insulation, potentially making individuals more sensitive to ambient temperature changes