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Gum inflammation and bleeding seem to increase in some GLP-1 users, possibly related to changes in immune function, blood flow, or bacterial populations in the mouth

Severe dizziness or fainting episodes are not normal side effects

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But retatrutide adds a direct hepatic mechanism on top of those indirect benefits

By contrast, countries like India, which do not award patent term extensions, could see generic competition entering much sooner once the patents on the main compound expire there in 2026