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61 Medullary thyroid cancer There is a theoretical increased risk of medullary thyroid cancer (MTC) as preclinical studies showed a link between GLP-1 receptor agonism to the development of C-cell hyperplasia and MTC in rodents

Atherosclerosis is a condition where the blood vessels get diseased over time as a result of risk factors like smoking, diabetes, and high cholesterol

Weight regain varies individually but typically begins within 2 weeks and averages 1 to 2 pounds weekly during the first month

Behavioural support , including referral to NHS weight management services or a dietitian, may be appropriate for patients who are struggling

This GLP-1/dexamethasone conjugate improved the body weight lowering potency of the GLP-1 analog alone, partially by alleviating surrogate markers of hypothalamic inflammation