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[23] [26] Current evidence is insufficient to establish efficacy, optimal dosing, or safety profiles in RA populations without diabetes or obesity

Why GLP-1s alone can lead to weight regain Microdosing lowers appetite, but it doesnt teach you how to eat or live differently

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Purifying long peptides is difficult, plus these GLP-1 peptide drugs have been modified to include a fatty acid side chain, and lipids themselves can be very difficult to purify, because theyre very hydrophobic, and tend to stick to the [purification] column, says Levine